The Ontario Telestroke Program (OTP) is a critical virtual care infrastructure in the provincial stroke system enabling access to hyperacute stroke care [i.e. tissue plasminogen activator (tPA) and endovascular thrombectomy (EVT)] in rural and remote areas of the province. Through an on-call consultation model of stroke neurologists, emergency departments across 31 telestroke hospitals can ensure timely assessment and delivery of hyperacute stroke services for the communities they serve. CorHealth Ontario, working closely with the Ontario Telemedicine Network (OTN), CritiCall Ontario, and other key stroke system stakeholders, has developed a framework to support measurement and reporting on key process and outcome indicators to enable a better understanding of the quality, infrastructure and population served by the Program. Activity is well underway to develop cohort definitions and indicator specifications to enable production of a baseline report early next fiscal.